The possible role of myocardial biopsy in systemic sclerosis.
Rheumatology (Oxford)
; 39(6): 674-9, 2000 Jun.
Article
em En
| MEDLINE
| ID: mdl-10888714
ABSTRACT
The histopathological features of heart involvement in systemic sclerosis (SSc) are not widely known. In internal and transplantation medicine, myocardial biopsies are increasingly used to diagnose cardiomyopathies including myocarditis. In two SSc patients presenting with dyspnoea with no evidence of pulmonary involvement, the cause of the compromised heart function was sought by myocardial biopsy. Immunohistological analysis revealed an increased number of CD3+ + T cells indicating myocarditis in one, and increased amounts of fibroblasts in both SSc patients. The authors think that myocardial involvement in SSc should be differentially evaluated and they propose the use of myocardial biopsies as a tool to distinguish between inflammatory and fibrotic forms of heart involvement in SSc patients.
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Base de dados:
MEDLINE
Assunto principal:
Escleroderma Sistêmico
/
Miocárdio
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Rheumatology (Oxford)
Assunto da revista:
REUMATOLOGIA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Alemanha