Triclabendazole in the treatment of human fascioliasis: a community-based study.
East Mediterr Health J
; 5(5): 888-94, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10983527
ABSTRACT
The efficacy of triclabendazole in the treatment of chronic Fasciola infection was assessed. A total of 134 asymptomatic cases of established Fasciola infection were treated 68 individuals received a single dose of 10 mg/kg and 66 individuals received 2 doses of 10 mg/kg on 2 consecutive days. Cure was assessed 5 weeks after treatment and 79.4% of the first group and 93.9% of the second group were cured. The drug was well tolerated; no serious side-effects were noted. One patient developed biochemical cholestasis the third day after treatment, but her enzyme profiles returned to normal after 2 months. We conclude triclabendazole is a safe and potent fasciolicidic drug.
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Base de dados:
MEDLINE
Assunto principal:
Benzimidazóis
/
Fasciolíase
/
Anti-Helmínticos
Tipo de estudo:
Clinical_trials
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Africa
Idioma:
En
Revista:
East Mediterr Health J
Assunto da revista:
MEDICINA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Egito