High F-18 FDG uptake in a low-grade supratentorial ganglioma: a positron emission tomography case report.
Clin Nucl Med
; 25(9): 694-7, 2000 Sep.
Article
em En
| MEDLINE
| ID: mdl-10983756
ABSTRACT
PURPOSE:
Positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (F-18 FDG) is used for the noninvasive monitoring and grading of primary brain tumors. Here the FDG uptake is positively correlated with the malignant extent of the lesion and thereby negatively correlated with patient survival. Little is known about the FDG PET features of primary brain tumors in children, such as mixed neuronal-glial tumors.METHODS:
The authors describe a 13-year-old boy who had partial complex seizures since early childhood caused by a brain tumor in the left temporal lobe.RESULTS:
Magnetic resonance and computed tomographic examinations yielded uncharacteristicresults:
mixed density, marked calcifications, little contrast enhancement, a nearly absent mass effect, and no edema. The FDG PET scan revealed a large hypermetabolic tumor, with a tumor contralateral gray matter FDG uptake ratio of 1.45. In contrast to this intense hypermetabolism, the pathologic analysis after gross total resection revealed a low-grade ganglioglioma (WHO grade 1), which is usually associated with an excellent prognosis.CONCLUSIONS:
Mixed neuronal-glial tumors such as gangliogliomas must be considered in making differential diagnoses by judging hypermetabolic FDG PET scans in young patients with brain tumors in the presence of uncharacteristic imaging features.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Supratentoriais
/
Ganglioglioma
/
Compostos Radiofarmacêuticos
/
Fluordesoxiglucose F18
Tipo de estudo:
Prognostic_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Clin Nucl Med
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Alemanha