Physiological regulation of uteroglobin/CCSP expression.
Ann N Y Acad Sci
; 923: 181-92, 2000.
Article
em En
| MEDLINE
| ID: mdl-11193756
ABSTRACT
Uteroglobin/CCSP is expressed specifically in the Clara cells. This allows the gene to be used as a marker to identify the elements regulating the physiologic and cell-specific expression of this gene. The regulation of UG/CCSP by IFN-gamma was shown to be at the level of the proximal promoter by the upregulation of HNF3 beta. This has allowed the determination of the factors responsible for the expression of UG/CCSP.
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Base de dados:
MEDLINE
Assunto principal:
Uteroglobina
/
Proteínas
/
Regulação da Expressão Gênica
/
Mucosa Respiratória
/
Pulmão
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Ann N Y Acad Sci
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos