Tolerance of efavirenz in children.
AIDS
; 15(2): 241-3, 2001 Jan 26.
Article
em En
| MEDLINE
| ID: mdl-11216933
ABSTRACT
OBJECTIVE:
To extend the limited knowledge of efavirenz tolerance in children.METHOD:
An observational study of 33 children given efavirenz combined with various others agents and followed in a single institution.RESULTS:
Fifteen (42%) of the children presented at least one clinically discernable side effect, cutaneous (n = 5), nervous system (n = 10), or both (n = 2). Intolerance led to treatment interruption in seven children but the main symptom was transitory dizziness or other signs similar to those observed in adults.CONCLUSION:
Early, often transient nervous system side effects require careful preparation with the child and his family to avoid premature and inadequate withdrawal from treatment.
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Base de dados:
MEDLINE
Assunto principal:
Oxazinas
/
Infecções por HIV
/
Inibidores da Transcriptase Reversa
/
Fármacos Anti-HIV
Tipo de estudo:
Observational_studies
Limite:
Adolescent
/
Child
/
Humans
Idioma:
En
Revista:
AIDS
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
França