Effects of Inula viscosa leaf extracts on abortion and implantation in rats.
J Ethnopharmacol
; 77(1): 117-21, 2001 Sep.
Article
em En
| MEDLINE
| ID: mdl-11483388
ABSTRACT
The anti-implantation and mid-term abortifacient effects exhibited by administration of Inula viscosa leaf extracts, were studied in rats. The aqueous extract administered i.p. on day 1-6 of gestation, totally diminished fetal implantation and caused a significant (P<0.05) reduction in the number of corpora lutea and blood progesterone levels. Meanwhile, administration on day 13-15 of gestation exhibited mid-term abortion. Furthermore, petroleum ether and dichloromethane, but not methanol, extracts exhibited pronounced abortifacient effects. The results of this study are in agreement with the traditional reputation of this plant as abortifacient. Further, the plant possesses anti-implantational and luteolytic effects.
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Base de dados:
MEDLINE
Assunto principal:
Abortivos
/
Extratos Vegetais
/
Magnoliopsida
Limite:
Animals
/
Pregnancy
Idioma:
En
Revista:
J Ethnopharmacol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Jordânia