Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride.
Acta Crystallogr C
; 58(Pt 1): o19-21, 2002 Jan.
Article
em En
| MEDLINE
| ID: mdl-11781483
ABSTRACT
The crystal structures of 8-hydroxy-5-nitroquinoline, C9H6N2O3, (I), and 8-hydroxy-5-nitroquinolinium chloride, C9H7N2O3+*Cl-, (II), have been determined from X-ray powder data. In (I), the molecules are linked via moderately strong hydrogen bonds to form dimers. Such a packing motif is likely to be responsible for the low solubility of (I) in water. In (II), the inversion-related cations form stacks, and anions fill the interstack channels.
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Base de dados:
MEDLINE
Assunto principal:
Anti-Infecciosos
/
Antifúngicos
/
Nitroquinolinas
Idioma:
En
Revista:
Acta Crystallogr C
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Federação Russa