Reversible aphasic disorder induced by lamotrigine in atypical benign childhood epilepsy.
Epileptic Disord
; 3(4): 217-22, 2001 Dec.
Article
em En
| MEDLINE
| ID: mdl-11844717
ABSTRACT
PURPOSE:
We studied an eleven year-old girl with atypical, benign partial epilepsy who acutely presented a severe aphasia associated with marked EEG deterioration after lamotrigine administration. A parallel monitoring of language disorders and EEG changes during the gradual withdrawal of lamotrigine was performed in order to evaluate their possible correlation with lamotrigine administration.METHODS:
Detailed neuropsychological and linguistic examinations in association with awake and sleep EEG were periodically performed.RESULTS:
The evolution of the aphasic disorder was closely related to the EEG abnormalities, and disappeared after the withdrawal of lamotrigine.CONCLUSIONS:
We considered the hypothesis that our case could be an expression of a paradoxical reaction to lamotrigine, in which the transitory aphasic disorder was sustained by an epileptiform electric activation.
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Base de dados:
MEDLINE
Assunto principal:
Afasia
/
Triazinas
/
Epilepsia Tipo Ausência
/
Anticonvulsivantes
Limite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
Epileptic Disord
Assunto da revista:
CEREBRO
/
NEUROLOGIA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Itália