Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency.
Mayo Clin Proc
; 77(3): 291-4, 2002 Mar.
Article
em En
| MEDLINE
| ID: mdl-11888035
ABSTRACT
Vitamin B12 deficiency is common, with most patients lacking classic features of advanced severe deficiency. Early diagnosis and treatment prevent severe anemia and irreversible damage to the nervous system. We describe a 34-year-old man with pernicious anemia who presented with clinical and radiologic features of early myelopathy and borderline low serum levels of vitamin B12. Prompt diagnosis based on the measurement of serum methylmalonic acid and treatment with cyanocobalamin injections led to rapid resolution of clinical manifestations and magnetic resonance imaging abnormalities. We review the literature of magnetic resonance imaging in vitamin B12 deficiency myelopathy and discuss the issues relating to diagnosis and early treatment of this potentially reversible condition.
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Base de dados:
MEDLINE
Assunto principal:
Parestesia
/
Doenças da Medula Espinal
/
Deficiência de Vitamina B 12
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Mayo Clin Proc
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos