CNTF is specifically expressed in developing rat pineal gland and eyes.
Neuroreport
; 13(5): 735-9, 2002 Apr 16.
Article
em En
| MEDLINE
| ID: mdl-11973480
ABSTRACT
Ciliary neurotrophic factor (CNTF) attracts considerable attention because it supports survival and differentiation of various types of neurons and glial cells in vitro. Although CNTF functions as a moderate neurotrophic factor in mature motor neurons, its role in embryonic development remains unknown. Here, we found a specific CNTF expression in the rat pineal gland and eyes during embryonic development. In vitro, neonatal rat pineal extract including CNTF supported the survival of neonatal sympathetic neurons, which innervate pineal glands immediately after birth.
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Base de dados:
MEDLINE
Assunto principal:
Glândula Pineal
/
Fator Neurotrófico Ciliar
/
Olho
Limite:
Animals
Idioma:
En
Revista:
Neuroreport
Assunto da revista:
NEUROLOGIA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Japão