Analytical methods for the monitoring of solid phase organic synthesis.
Farmaco
; 57(6): 497-510, 2002 Jun.
Article
em En
| MEDLINE
| ID: mdl-12088065
Solid phase synthesis (SPS) is a powerful technique to assemble compound libraries in high-throughput parallel and combinatorial synthesis. The widespread applications of these techniques required the development of analytical methods for both structural elucidation and reaction monitoring. This review covers some recently developed techniques for on-bead analyses together with solution-state ones. Particular emphasis is devoted to software and hardware improvements for automated high-throughput analysis.
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Base de dados:
MEDLINE
Assunto principal:
Técnicas de Química Analítica
/
Química Orgânica
/
Técnicas de Química Combinatória
Idioma:
En
Revista:
Farmaco
Assunto da revista:
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Itália