[Giant cell arteritis after the age of 75]. / Maladie de Horton chez le sujet âgé de plus de 75 ans.
Ann Med Interne (Paris)
; 153(6): 373-7, 2002 Oct.
Article
em Fr
| MEDLINE
| ID: mdl-12486385
ABSTRACT
Despite its increasing incidence giant cell arteritis is not well detected in the elderly. Response to corticosteroid treatment is the same before and after the age of 75, but there are many steroid-induced side effects, particularly bone fractures, in the elderly. Therefore, it is important to reduce the corticosteroid load in elderly and frail people. In this cases, 0.3 to 0.5mg/kg, or 15 to 25mg daily prednisone-equivalent dose at start seems to be enough to prevent blindness in simple forms. This dose has to be rapidly reduced whenever the C-reactive protein remains moderately elevated. Moreover, an anti-agregant or anticoagulant treatment must be associated at the beginning of steroid treatment to prevent ischemic complications, as well as biphosphonates, which could prevent corticosteroid-induced osteoporosis.
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Base de dados:
MEDLINE
Assunto principal:
Arterite de Células Gigantes
/
Prednisona
/
Anti-Inflamatórios não Esteroides
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Ann Med Interne (Paris)
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
França