Genetics (molecular biology) and Meniere's disease.
Otolaryngol Clin North Am
; 35(3): 497-516, 2002 Jun.
Article
em En
| MEDLINE
| ID: mdl-12486836
ABSTRACT
COCH is not the FMD gene detected in our linkage study; furthermore, COCH and FMD are not allelic. The indications are that FMD is heterogenetic. The linkage analysis points to the possibility of one FMD mutation in one of the neighboring candidate genes on chromosome 14, and, with anticipation, possibly a triple repeat amplification. Recently, the myotonic dystrophy type 2 locus has been shown to contain an expanded tetranucleotide repeat [46], so the search for a similar repeat on 14q is indicated.
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Base de dados:
MEDLINE
Assunto principal:
Doença de Meniere
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Animals
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Otolaryngol Clin North Am
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Reino Unido