TT virus loads and lymphocyte subpopulations in children with acute respiratory diseases.
J Virol
; 77(16): 9081-3, 2003 Aug.
Article
em En
| MEDLINE
| ID: mdl-12885924
ABSTRACT
TT virus (TTV) produces chronic plasma viremia in around 90% of healthy individuals of all ages and has, therefore, been proposed as a commensal human virus. We recently demonstrated that in children hospitalized for acute respiratory diseases high TTV loads were associated with severe forms of disease. Here, we report that in such children TTV loads showed an inverse correlation with the percentage of circulating total T and helper T cells and a direct correlation with the percentage of B cells. Thus, florid TTV replication might contribute to lymphocyte imbalances and, possibly, immunosuppressive effects, thus resembling related animal viruses.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Respiratórias
/
Subpopulações de Linfócitos
/
Carga Viral
/
Torque teno virus
Limite:
Child
/
Humans
Idioma:
En
Revista:
J Virol
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Itália