Clinical anophthalmia: an epidemiological study in northeast Italy based on 368,256 consecutive births.
Teratology
; 46(6): 551-3, 1992 Dec.
Article
em En
| MEDLINE
| ID: mdl-1290155
ABSTRACT
We describe an epidemiological and clinical study of Clinical Anophthalmia in a population of consecutive live and stillborns enrolled in a hospital based registry of congenital malformations in Northeast Italy during the period from 1981 to 1989; 22 cases were detected among 368,256 births yielding a birth prevalence of 0.60 per 10,000 (95% CI 0.34-0.84); 20 cases were associated with at least one other major malformation. Malformation syndrome, association, or sequence was diagnosed in 13, while a non-recognizable multiple defect pattern was observed in 7/20 (35%). A chromosomal anomaly was present in eight syndromic cases. No significant trend over time, nor space or time clusters, were detected. As most CAn cases are associated with other anomalies recognizable by ultrasound, a decreasing trend in its prevalence at birth is expected in the future.
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Base de dados:
MEDLINE
Assunto principal:
Anormalidades Múltiplas
/
Anoftalmia
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Teratology
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Itália