Safety of fluoroquinolones in paediatrics.
Expert Opin Drug Saf
; 1(4): 319-24, 2002 Nov.
Article
em En
| MEDLINE
| ID: mdl-12904131
ABSTRACT
In the last few years, there has been increasing pressure to use fluoroquinolones in paediatric patients, since these antibiotics offer the advantage of an oral treatment regimen on an out-patient basis. However, even although this class of antibiotics generally remains well-tolerated, the restriction of fluoroquinolone use in children on a compassionate basis, which derives from their potential to cause cartilage toxicity, limits the safety data in this population and suggests a cautious use. This review reports the data of the literature on the safety of fluoroquinolones in different districts, focusing on the side effects in children and drug interactions. Moreover, data available in the literature with regards to side effects in children are reported, with particular attention to their potential in arthropathy.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Artropatia Neurogênica
/
Hipersensibilidade a Drogas
/
Anti-Infecciosos
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Expert Opin Drug Saf
Assunto da revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Itália