Detection of herpes simplex virus type-2 DNA and human papilloma virus DNA sequences in cervical carcinoma tissue by molecular hybridization.
J Exp Pathol
; 6(1-2): 55-64, 1992.
Article
em En
| MEDLINE
| ID: mdl-1320668
ABSTRACT
Biopsy samples from one hundred and two patients with squamous cell carcinoma of the uterine cervix and tissues from twelve healthy normal cervical tissues (post hysterectomy) were examined for HSV-type 2 and HPV-11 DNA sequences by molecular hybridization technique. In the carcinoma tissue extracts 53% contained HSV-2 DNA, 27% -HSV-1-DNA and 36% showed HPV-11 gene sequences while 5.7% were found to contain both HPV and HSV-2 DNA. Biopsies from healthy cervix were completely negative for HSV-2 and HPV-11 DNA sequences.
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Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
DNA Viral
/
Neoplasias do Colo do Útero
/
Simplexvirus
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
Idioma:
En
Revista:
J Exp Pathol
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Índia