Incidence of cancer among UK Gulf war veterans: cohort study.
BMJ
; 327(7428): 1373, 2003 Dec 13.
Article
em En
| MEDLINE
| ID: mdl-14670879
ABSTRACT
OBJECTIVES:
To determine whether incidence rates of cancer are higher in UK service personnel who were deployed in the Gulf war than in those not deployed and whether any increased risk of cancer is related to self reported exposures to potentially hazardous material during the period of deployment.DESIGN:
A cohort study with follow up from 1 April 1991 (the end of the Gulf war) to 31 July 2002.PARTICIPANTS:
51 721 Gulf war veterans and 50 755 service personnel matched for age, sex, rank, service, and level of fitness who were not deployed in the Gulf (the Era cohort). MAIN OUTCOMEMEASURES:
Incident cancers, identified on the NHS central register.RESULTS:
There were 270 incident cancers among the Gulf cohort and 269 among the Era cohort (incidence rate ratio 0.99, 95% confidence interval 0.83 to 1.17). There was no excess in site specific cancers among the Gulf cohort. Adjustment for lifestyle factors (smoking and alcohol consumption) did not alter these results. In the Gulf cohort, risk of cancer was not related to multiple vaccinations or exposure to pesticides or depleted uranium during deployment.CONCLUSION:
There is no current excess risk of cancer overall nor of site specific cancers in Gulf war veterans. Specific exposures during deployment have not resulted in a subsequent increased risk of cancer. The long latent period for cancer, however, necessitates the continued follow up of these cohorts.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Guerra
/
Militares
/
Neoplasias
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
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Female
/
Humans
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Male
/
Middle aged
País/Região como assunto:
Asia
/
Europa
Idioma:
En
Revista:
BMJ
Assunto da revista:
MEDICINA
Ano de publicação:
2003
Tipo de documento:
Article