Association between maternal-fetal Doppler velocimetry and fetal lung maturity.
J Perinat Med
; 31(6): 484-8, 2003.
Article
em En
| MEDLINE
| ID: mdl-14711104
ABSTRACT
AIMS:
To correlate maternal-fetal Doppler velocimetry parameters to indices of fetal lung maturity (FLM).METHODS:
Fifty-five consecutive third trimester pregnancies in which a pulsed-wave Doppler study, including uterine resistance index (Ut RI), umbilical artery pulsatility index (UA PI), middle cerebral artery pulsatility index (MCA PI) and the UA/MCA ratio was performed within 24 hours before amniocentesis and within a week from birth. FLM was determined by amniotic fluid lamellar bodies count (LBs).RESULTS:
A positive correlation between MCA PI and LBs (p < 0.007, r = 0.44) was found. MCA PI showed a trend to lower values in fetuses that developed RDS at birth (1.3 +/- 0.5 vs. 1.7 +/- 0.4, NS). LBs significantly decreased as Ut RI increased (O.R. 0.98, C.I. 0.97-0.99, p < 0.05). A mean Ut RI > 0.64 was correlated to delayed FLM (LBs < 20,000/microl; sensitivity 90.9%, specificity 90.3%; positive predictive value 76.9%, negative predictive value 96.6%).COMMENT:
In third trimester pregnancies abnormal uterine artery waveforms may be associated to a delayed FLM, as expressed by decreased amniotic fluid LBs.
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Base de dados:
MEDLINE
Assunto principal:
Útero
/
Ultrassonografia Doppler de Pulso
/
Maturidade dos Órgãos Fetais
/
Feto
/
Pulmão
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Perinat Med
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Itália