Social aspects of genetic testing for factor V Leiden mutation in healthy individuals and their importance for daily practice.
Thromb Res
; 113(1): 7-12, 2004.
Article
em En
| MEDLINE
| ID: mdl-15081560
ABSTRACT
To explore social aspects of asymptomatic carriership of factor V Leiden mutation (FVL) and how carriers have experienced procedure of screening for FVL, we have performed a qualitative study using semi-structured interviews. Seventeen carriers of FVL without history of venous thromboembolism (VTE) were interviewed. Carriership of FVL has the potential to influence daily life by inducing concerns, stigmatisation and problems with insurances. Furthermore, proper procedure of screening is important because carriers have many questions concerning progeny, risk factors for VTE and preventive measures. Both health worker and the individual to be screened for FVL need to be fully aware of the possible consequences of screening and the fact that proper screening comprises more than only the collection of a blood sample or explaining the amount of risk for VTE induced by a genetic defect. Any guideline to be developed for the screening for FVL should take this into account too.
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Base de dados:
MEDLINE
Assunto principal:
Fator V
/
Testes Genéticos
/
Conhecimentos, Atitudes e Prática em Saúde
/
Triagem de Portadores Genéticos
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Qualitative_research
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Thromb Res
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Holanda