Cutaneous ulcers: An unusual manifestation of inherited thrombophilia.
Am J Hematol
; 76(2): 139-42, 2004 Jun.
Article
em En
| MEDLINE
| ID: mdl-15164379
ABSTRACT
We report two cases with cutaneous lesions found to be associated with factor V Leiden mutation and low S protein levels. At the time of presentation, no other symptoms were reported. Histopathology of both lesions revealed the presence of widespread intravascular thrombi. The therapeutic response to oral anticoagulants in the first case was dramatic, leading to complete healing of the lesions. Inherited causes of thrombophilia manifested as cutaneous lesions, although rare, should be considered in the differential diagnosis of occlusive vasculopathy.
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Base de dados:
MEDLINE
Assunto principal:
Úlcera Cutânea
/
Trombofilia
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Hematol
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Grécia