Upregulation of mRNA expression of vascular endothelial growth factor and its receptors by exogenous human chorionic gonadotropin in cultured oviduct mucosal cells.
Fertil Steril
; 82(6): 1708-10, 2004 Dec.
Article
em En
| MEDLINE
| ID: mdl-15589889
ABSTRACT
The mucosal cells were isolated from the ampullary regions of 20 human oviducts and cultured with or without hCG in five different concentrations (1-100 ng/mL). As analyzed by the semiquantitative reverse-transcriptase polymerase chain reaction, hCG treatment significantly increased mRNA expression of vascular endothelial growth factor and its receptor flt-1 in the cultured mucosal cells in a dose-dependent manner but had no effect on the expression of another receptor, KDR.
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Base de dados:
MEDLINE
Assunto principal:
Regulação para Cima
/
Receptor 1 de Fatores de Crescimento do Endotélio Vascular
/
Fator A de Crescimento do Endotélio Vascular
/
Tubas Uterinas
/
Gonadotropina Coriônica
Limite:
Female
/
Humans
Idioma:
En
Revista:
Fertil Steril
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
China