Elimination of Pancoast tumor by carboplatin, paclitaxel, and concurrent radiation.
Jpn J Thorac Cardiovasc Surg
; 52(11): 534-7, 2004 Nov.
Article
em En
| MEDLINE
| ID: mdl-15609647
ABSTRACT
Preoperative chemoradiotherapy with carboplatin (AUC 1.5), paclitaxel (40 mg/m2), and concurrent extracorporeal radiation (40 Gy) was used to treat a Pancoast tumor (clinical T3N0M0), without causing adverse events. Then left upper lobectomy was performed along with mediastinal lymph node dissection plus resection of the chest wall and Th1 nerve root. Histological examination revealed a pathological complete response. This multimodal regimen was feasible and achieved a good response, so it seems worthwhile to evaluate the clinical effectiveness of the therapy in a cohort study.
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Base de dados:
MEDLINE
Assunto principal:
Síndrome de Pancoast
/
Protocolos de Quimioterapia Combinada Antineoplásica
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Jpn J Thorac Cardiovasc Surg
Assunto da revista:
ANGIOLOGIA
/
CARDIOLOGIA
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Japão