Intranasal apomorphine in parkinsonian on-off fluctuations.
Arch Neurol
; 49(5): 482-4, 1992 May.
Article
em En
| MEDLINE
| ID: mdl-1580809
ABSTRACT
The efficacy of intranasal apomorphine was assessed in seven patients with Parkinson's disease and severe levodopa (L-dopa)-related "off-period" disabilities. All patients responded favorably to treatment with intranasal apomorphine. The speed and the quality of motor response and the pharmacokinetic profile showed results similar to those seen after subcutaneous injection of apomorphine administered by insulin pen syringe. The simplicity in the technique of intranasal apomorphine administration was found to be superior by all patients.
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Apomorfina
Limite:
Adult
/
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
Arch Neurol
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Holanda