An amperometric glucose biosensor based on glucose oxidase immobilized in electropolymerized poly(o-aminophenol) and carbon nanotubes composite film on a gold electrode.
Anal Sci
; 21(4): 367-71, 2005 Apr.
Article
em En
| MEDLINE
| ID: mdl-15844327
ABSTRACT
An amperometric glucose biosensor is developed that is based on immobilization of glucose oxidase (GOD) in a composite film of poly(o-aminophenol) (POAP) and carbon nanotubes (CNT), which are electrochemically co-polymerized at a gold (Au) electrode. Because of the high surface per volume ratio and excellent electrical conductivity of CNT, the biosensor based on an Au/POAP/CNT/GOD electrode has lower detection limit (0.01 mM), larger maximum response current (0.24 mA cm(-2)) and higher sensitivity (11.4 mA M(-1) cm(-2)) than the values of the biosensor based on an Au/POAP/GOD electrode. Additionally, the biosensor shows fast response time, large response current, and good anti-interferent ability for ascorbic acid, uric acid and acetaminophen. Good reproducibility and stability of the biosensor are also observed.
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Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Técnicas Biossensoriais
/
Glucose
/
Glucose Oxidase
Idioma:
En
Revista:
Anal Sci
Ano de publicação:
2005
Tipo de documento:
Article