Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI.
Med Phys
; 32(4): 1128-39, 2005 Apr.
Article
em En
| MEDLINE
| ID: mdl-15895597
ABSTRACT
We employ diffuse optical tomography (DOT) to track treatment progress in a female subject presenting with locally advanced invasive carcinoma of the breast during neoadjuvant chemotherapy. Three-dimensional images of total hemoglobin concentration and scattering identified the tumor. Our measurements reveal tumor shrinkage during the course of chemotherapy, in reasonable agreement with magnetic resonance images of the same subject. A decrease in total hemoglobin concentration contrast between tumor and normal tissue was also observed over time. The results demonstrate the potential of DOT for measuring physiological parameters of breast lesions during chemotherapy.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Imageamento por Ressonância Magnética
/
Quimioterapia Adjuvante
/
Carcinoma Ductal de Mama
/
Tomografia Óptica
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Med Phys
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos