Synthesis of allenamides by copper-catalyzed coupling of allenyl halides with amides, carbamates, and ureas.

ABSTRACT

[reaction see text]. A variety of N-substituted allenes have been synthesized by the copper-catalyzed coupling reaction between allenyl halides and amides, carbamates, and ureas. The reactions proceed in good to excellent yield using 7 mol % copper thiophenecarboxylate and 15 mol % of a diamine catalyst.