A novel simian immunodeficiency virus from black mangabey (Lophocebus aterrimus) in the Democratic Republic of Congo.
J Gen Virol
; 86(Pt 7): 1967-1971, 2005 Jul.
Article
em En
| MEDLINE
| ID: mdl-15958675
ABSTRACT
In order to understand primate lentivirus evolution, characterization of additional simian immunodeficiency virus (SIV) strains is essential. Here, an SIV from a black mangabey (Lophocebus aterrimus) originating from the Democratic Republic of Congo was analysed phylogenetically. The monkey had cross-reactive antibodies against human immunodeficiency virus type 1 (HIV-1) and HIV-2. The viral pol region sequence was amplified by nested PCR and sequence analysis confirmed that it was related to known SIV sequences. This is the first report to characterize genetically an SIV from the monkey genus Lophocebus. Phylogenetic analysis of the pol region revealed that this novel SIV, designated SIVbkm, fell into the SIVsyk and SIVgsn virus group, containing viruses isolated from the genus Cercopithecus, and suggests that cross-species transmission has occurred between species of the genera Lophocebus and Cercopithecus.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Filogenia
/
Síndrome de Imunodeficiência Adquirida dos Símios
/
Vírus da Imunodeficiência Símia
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Cercocebus
Limite:
Animals
/
Humans
País/Região como assunto:
Africa
Idioma:
En
Revista:
J Gen Virol
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Japão