Secondary hormonal manipulations in the management of advanced prostate cancer.
Can J Urol
; 12(3): 2666-76, 2005 Jun.
Article
em En
| MEDLINE
| ID: mdl-16011813
ABSTRACT
Prostate cancer is a heterogeneous disease and clinical outcomes vary considerably after failure of primary androgen ablation. With the development of new therapeutics the management of patients with androgen independent prostate cancer has changed considerably over the last few years. Multiple secondary hormonal manipulations are available and may lead to prolonged periods of clinical response. These maneuvers include the use of oral antiandrogens, antiandrogen withdrawal, ketoconazole, aminoglutethimide, corticosteroids and use of estrogenic compounds. This article reviews the clinical activity of these agents in management of patients with advanced prostate cancer.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Antineoplásicos Hormonais
/
Androgênios
Limite:
Humans
/
Male
Idioma:
En
Revista:
Can J Urol
Assunto da revista:
UROLOGIA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos