Forensic potential of the STR DXYS156 in Mexican populations: inference of X-linked allele null.
Leg Med (Tokyo)
; 8(1): 52-4, 2006 Jan.
Article
em En
| MEDLINE
| ID: mdl-16213776
ABSTRACT
The pentanucleotide STR (TAAAA)n DXYS156 offers advantages for genetic identity testing. In addition to establish the gender, DXYS156 expands the DNA profile and is able to indicate the possible geographic origin of the individual. We analyzed DXYS156 in 757 individuals of both sexes from Mexican populations. We studied the cosmopolitan Mestizo population and six Mexican ethnic groups Tarahumaras, Purépechas, Nahuas, Mayas, Huicholes and Mezcala Indians. The six shorter (4-10) and the three larger alleles (11-13) were specific for the X and Y-chromosomes, respectively. A random distribution of alleles into genotypes was observed in males and females from each population. We estimated the power of exclusion for paternity testing according to the son's gender, and the power of discrimination in forensic casework. In addition, we detected a relatively high frequency of an X-linked allele null, principally in Mexican-Mestizos (3.6%), which must be considered when DXYS156 be applied for identification purposes.
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Base de dados:
MEDLINE
Assunto principal:
Sequências de Repetição em Tandem
/
Cromossomos Humanos X
/
Frequência do Gene
/
Genética Populacional
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Leg Med (Tokyo)
Assunto da revista:
JURISPRUDENCIA
Ano de publicação:
2006
Tipo de documento:
Article