[Individual digital design and functional reconstruction of large mandibular defect with computer-aided design/computer aided manufacture technique].

ABSTRACT

OBJECTIVE: To build up a new contour and functional reconstruction technique of mandibular defects with rapid prototyping and reverse engineering technique. METHODS: From April 2002 to August 2004, 4 cases of mandibular defects due to resection of large mandible lesion were treated. Of 4 patients, there were 3 females and 1 male, with an age range of 21-42 years, which underwent secondary operation and presented a deviation as mandibular movement. The opening-mouth extent was 1.8-2.5 cm (2.2 cm on average). The data of defects area were renewed with Mimics and Geomagic Studio software; and the titanium reconstructive frame was designed and manufactured with rapid prototyping technique. Defect were reconstructed by using CT digital data of patients. RESULTS: The CT data could be used by image software directly. The implant design could be completed by computer-aimed design (CAD) / computer-aided manufacture (CAM). The resin model and titanium frame were manufactured accurately by RP technique. Four patients achieved one stage healing. After a follow-up of 3 months to 2 years, large mandibular defect was reconstructed satisfactorily and the opening-mouth extent was 3.0-3.4 cm (3.2 cm on average). The occluding relation was normal. The implant denture was put on and the mastication function was good in 1 case. CONCLUSION: Individual design and repair of large mandibular defect with CAD/CAM techniques is worth extending application clinically. It is a simple and accurate method.