Effects of blocking nitric oxide on learning in turtles (Chrysemys picta).
Behav Neurosci
; 119(6): 1656-61, 2005 Dec.
Article
em En
| MEDLINE
| ID: mdl-16420168
ABSTRACT
Turtles (Chrysemys picta) were given the nitric oxide synthase inhibitor NW-nitro-L-arginine methyl ester (L-NAME) or its inactive isomer NW-nitro-D-arginine methyl ester (D-NAME) and were trained on a negative patterning task or a simple go/no-go discrimination task. L-NAME impaired the learning of negative patterning but did not affect retention of the task if it had already been learned. D-NAME had no effect. Go/no-go discrimination learning was not affected by L-NAME. These findings support the notion that nitric oxide plays a role in complex configural learning in a reptile closely related to the ancestors of mammals.
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Base de dados:
MEDLINE
Assunto principal:
Tartarugas
/
NG-Nitroarginina Metil Éster
/
Aprendizagem
/
Óxido Nítrico
Limite:
Animals
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos