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Current understanding of the aetiology and laboratory diagnosis of footrot.
Wani, S A; Samanta, I.
Afiliação
  • Wani SA; Division of Veterinary Microbiology and Immunology, S.K. University of Agricultural Sciences and Technology of Kashmir, Shuhama (Alusteng), Srinagar, Kashmir 190006, India. microlab@sancharnet.in
Vet J ; 171(3): 421-8, 2006 May.
Article em En | MEDLINE | ID: mdl-16624707
ABSTRACT
Footrot is a highly contagious disease of the feet of ruminants caused by the synergistic action of certain bacterial species of which Dichelobacter nodosus (D. nodosus) is the main transmitting agent. The infection is specific to sheep and goats, although it has also been reported in cattle, horses, pigs, deer and mouflon. The antigenic diversity of D. nodosus is due to variations in the DNA sequence of its fimbrial subunit gene (fimA) and provides the basis for classification of the organism into at least 10 major serogroups (A-I and M), the distribution of which varies with different geographical locations. Host immune response to vaccination is serogroup specific. There are three different clinical forms of disease caused by virulent, intermediate and benign strains of D. nodosus, respectively. In order to facilitate rapid and reliable clinical diagnosis, virulence determination, strain differentiation and serogroup identification for effective control measures, immunological tests, DNA probes and PCR based techniques have been introduced. This review summarises the current understanding of the mechanisms of antigenic diversity of D. nodosus as well as advances made in its strain differentiation and diagnosis.
Assuntos
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Base de dados: MEDLINE Assunto principal: Doenças dos Ovinos / Variação Antigênica / Doenças das Cabras / Infecções por Bactérias Gram-Negativas / Dichelobacter nodosus / Pododermatite Necrótica dos Ovinos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Vet J Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Índia
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Base de dados: MEDLINE Assunto principal: Doenças dos Ovinos / Variação Antigênica / Doenças das Cabras / Infecções por Bactérias Gram-Negativas / Dichelobacter nodosus / Pododermatite Necrótica dos Ovinos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Vet J Assunto da revista: MEDICINA VETERINARIA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Índia