Bovine preantral follicles and activin: immunohistochemistry for activin and activin receptor and the effect of bovine activin A in vitro.
Theriogenology
; 48(1): 133-42, 1997 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-16728113
ABSTRACT
Activin was originally isolated from follicular fluid as a factor stimulating FSH from the pituitary. Recent studies also suggest a local role for activin in the development of preantral and early antral follicles. In the present study, activin and activin receptor immunoreactivity are shown in oocyte and granulosa cells of bovine preantral follicles. In addition, activin immunoreactivity was observed in the theca of secondary follicles. During culture of isolated preantral follicles, activin increased follicular growth and granulosa cell proliferation in a dose-dependent manner. This increase was further stimulated by addition of FSH. In conclusion, activin and its receptor are present on bovine preantral follicles, and additional activin stimulates development of those follicles.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Theriogenology
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Holanda