A retrospective study of clinical, physiologic and immunologic changes in workers exposed to toluene diisocyanate.
Am Ind Hyg Assoc J
; 36(3): 159-68, 1975 Mar.
Article
em En
| MEDLINE
| ID: mdl-167571
ABSTRACT
A retrospective study was made of workers in a toluene disocyanate plant using an immunologic test procedure developed at the NIOSH laboratories. Case histories of 32 workers in seven response groupings are presented. Sensitization was found to correlate with the frequency and severity of significant exposures to TDI. Immunologic changes producing tolerance to TDI exposure also resulted in negative response to the antigen challenge tests. Some individuals exposed to TDI may have protective antibodies but still experience bronchoconstriction.
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Base de dados:
MEDLINE
Assunto principal:
Hipersensibilidade Respiratória
/
Indústria Química
/
Tolueno 2,4-Di-Isocianato
/
Cianatos
/
Hipersensibilidade Tardia
/
Doenças Profissionais
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Revista:
Am Ind Hyg Assoc J
Ano de publicação:
1975
Tipo de documento:
Article