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Trabecular bone status in ultradistal tibia under habitual gait loading: a pQCT study in postmenopausal women.
Lai, Yau-Ming; Qin, Ling; Hung, Vivian Wing-Yin; Choy, Wing-Yee; Chan, Suk-Tak; Chan, Lawrence Wing-Chi; Chan, Kai-Ming.
Afiliação
  • Lai YM; Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, PR China.
J Clin Densitom ; 9(2): 175-83, 2006.
Article em En | MEDLINE | ID: mdl-16785078
ABSTRACT
This study investigated regional volumetric trabecular bone mineral density (tBMD) and bone area at the ultradistal tibia in Chinese women using peripheral quantitative computed tomography. Fifty-six postmenopausal women aged 47-62 yr participated in BMD measurements at baseline and 22 of them were followed at both 1-yr and 3-yr follow-up scans. Regional baseline tBMD, rate of annual bone loss, and trabecular bone area were determined. Baseline measurements showed that the tBMD of both the posterior (252.9+/-63.4 mg/cm(3)) and medial (226.6+/-68.9 mg/cm(3)) regions was significantly higher than that of the anterior (126.3+/-61.9 mg/cm(3)) and lateral regions (149.8+/-50.6 mg/cm(3)), respectively (p<0.001). Both the 1-yr and 3-yr follow-up measurements showed that there was significant physiological annual tBMD loss on an average of 1.61%, at the four regions. Inter-slice regional tBMD and trabecular bone area measurements demonstrated a significant linear decrease from the distal to proximal aspects (p<0.001). Findings suggest that dynamic compressive loading during the heel strike and the body weight vector shifting toward the medial aspect during the stance phase in a normal gait might account for the regional tBMD differences. Increased tBMD and bone area toward the distal tibial endplate may adapt to withstand the axial impact loading. However, the low-impact weight-bearing nature of a normal gait may not be osteogenic to prevent regional bone loss. An exercise program specific to the women at risk should be contemplated.
Assuntos
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Base de dados: MEDLINE Assunto principal: Tíbia / Densidade Óssea / Marcha Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Middle aged Idioma: En Revista: J Clin Densitom Assunto da revista: ORTOPEDIA Ano de publicação: 2006 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Tíbia / Densidade Óssea / Marcha Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Middle aged Idioma: En Revista: J Clin Densitom Assunto da revista: ORTOPEDIA Ano de publicação: 2006 Tipo de documento: Article