Rhodium(I)-catalyzed carboxylation of aryl- and alkenylboronic esters with CO2.
J Am Chem Soc
; 128(27): 8706-7, 2006 Jul 12.
Article
em En
| MEDLINE
| ID: mdl-16819845
ABSTRACT
When the esters of arylboronic acids with 2,2-dimethylpropan-1,3-diol were treated with a catalytic amount of [Rh(OH)(cod)]2 in the presence of 1,3-bis(diphenylphosphino)propane and CsF in dioxane at 60 degrees C under carbon dioxide atmosphere, the benzoic acid derivatives were obtained in good yields. Reactions of alkenylboronic esters also proceeded under similar conditions to give alpha,beta-unsaturated carboxylic acids. As these boronic esters are now easily available through coupling or direct borylation reactions, this method would be a useful method for the preparation of various functionalized aryl- and alkenyl-carboxylic acids.
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Base de dados:
MEDLINE
Assunto principal:
Ródio
/
Ácidos Borônicos
/
Dióxido de Carbono
/
Ácidos Carboxílicos
/
Ésteres
Idioma:
En
Revista:
J Am Chem Soc
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Japão