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[Effect of vasoactive intestinal peptide and epidermal growth factor on the adhesion of eosinophils to bronchial epithelial cells].
Li, Xiang; Xing, Xiu-mei; Zhang, Jian-song; Tan, Yu-rong.
Afiliação
  • Li X; Research Department of Applied Physiology, Medical College, Hunan Normal University, Changsha 410006, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 31(5): 772-5, 781, 2006 Oct.
Article em Zh | MEDLINE | ID: mdl-17062950
OBJECTIVE: To investigate the effect of intrapulmonary regulatory peptides on adhesion of eosinophils (EOS) to bronchial epithelial cells (BECs). METHODS: Two regulatory peptides, namely vasoactive intestinal peptide (VIP) and epidermal growth factor (EGF) were investigated. VIP and EGF were observed on the secretion of ILs and expression of intercellular adhesion molecule-1 (ICAM-1). RESULTS: VIP and EGF could decrease ILs secretion and ICAM-1 expression. CONCLUSION: VIP and EGF inhibited the adhesion of EOS to BEC in the inflammatory process to lighten the airway inflammation.
Assuntos
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Base de dados: MEDLINE Assunto principal: Brônquios / Peptídeo Intestinal Vasoativo / Eosinófilos / Fator de Crescimento Epidérmico / Células Epiteliais Limite: Animals Idioma: Zh Revista: Zhong Nan Da Xue Xue Bao Yi Xue Ban Assunto da revista: MEDICINA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: China
Buscar no Google
Base de dados: MEDLINE Assunto principal: Brônquios / Peptídeo Intestinal Vasoativo / Eosinófilos / Fator de Crescimento Epidérmico / Células Epiteliais Limite: Animals Idioma: Zh Revista: Zhong Nan Da Xue Xue Bao Yi Xue Ban Assunto da revista: MEDICINA Ano de publicação: 2006 Tipo de documento: Article País de afiliação: China