[Laboratory evolutive aspects of children under paracoccidioidomycosis treatment]. / Aspectos laboratoriais evolutivos de crianças em tratamento da paracoccidioidomicose.
Rev Soc Bras Med Trop
; 39(5): 478-83, 2006.
Article
em Pt
| MEDLINE
| ID: mdl-17160327
ABSTRACT
The study of 38 children with paracoccidioidomycosis, aged up to 14, treated for 24 to 30 months with either a sulfonamide derivative or ketoconazole either alone or, after the use of amphotericin B. Laboratory data at admission were analyzed and compared with those of sequential tests after up to 30 months follow-up. Anemia, eosinophilia, increased bilirubin and aminotransferases normalized, in most patients, after three months treatment and hypoalbuminemia normalized after six months, suggesting that these laboratory findings are useful for monitoring early therapeutic response. Peripheral leucocytes, erythrocyte sedimentation rate, IgG, and serological titers for Paracoccidioides brasiliensis were increased and frequently normalized after nine to 12 months of treatment. They may be useful for monitoring the entire treatment and emphasize the need for long term treatment of paracoccidioidomycosis in children.
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Base de dados:
MEDLINE
Assunto principal:
Paracoccidioidomicose
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adolescent
/
Child
/
Humans
Idioma:
Pt
Revista:
Rev Soc Bras Med Trop
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Madagascar