H1-antihistamines for the treatment of anaphylaxis with and without shock.
Cochrane Database Syst Rev
; (1): CD006160, 2007 Jan 24.
Article
em En
| MEDLINE
| ID: mdl-17253584
ABSTRACT
BACKGROUND:
Anaphylaxis is an acute systemic allergic reaction, which can be life-threatening. H1-antihistamines are commonly used as an adjuvant therapy in the treatment of anaphylaxis.OBJECTIVES:
To assess the benefits and harm of H1-antihistamines in the treatment of anaphylaxis. SEARCH STRATEGY We searched the Cochrane Central Register of Controlled Trials (CENTRAL), (The Cochrane Library), MEDLINE (1966 to June 2006);EMBASE (1966 to June 2006); CINAHL (1982 to June 2006) and ISI Web of Science (1945 to July 2006). We also contacted pharmaceutical companies and international experts in anaphylaxis in an attempt to locate unpublished material. SELECTION CRITERIA Randomized and quasi-randomized controlled trials comparing H1-antihistamines with placebo or no intervention. DATA COLLECTION ANDANALYSIS:
Two authors independently assessed articles for inclusion. MAINRESULTS:
We found no studies that satisfied the inclusion criteria. AUTHORS'CONCLUSIONS:
Based on this review, we are unable to make any recommendations for clinical practice. Randomized controlled trials are needed, although these are likely to prove challenging to design and execute.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Choque
/
Antagonistas dos Receptores Histamínicos H1
/
Anafilaxia
Tipo de estudo:
Clinical_trials
/
Guideline
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Cochrane Database Syst Rev
Assunto da revista:
PESQUISA EM SERVICOS DE SAUDE
Ano de publicação:
2007
Tipo de documento:
Article