Pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma.
Int J Hematol
; 85(2): 146-8, 2007 Feb.
Article
em En
| MEDLINE
| ID: mdl-17321993
ABSTRACT
Pasteurella (P) multocida exists in a variety of animals and causes diverse infections in humans due to animal bites and scratches, usually by cats or dogs, and oral and respiratory infection. We report a case of P multocida sepsis due to a scratch from a pet cat, complicated with disseminated intravascular coagulation in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma. The patient was a febrile 79-year-old woman with disturbed consciousness and subcutaneous abscess in her right hand due to a scratch from a pet cat. She was successfully treated with empirical antibiotic therapy with cefepime and administrations of granulocyte colony-stimulating factor and danaparoid. The minimum inhibitory concentration of cefepime against the isolate from this case was <2mg/L. Although a few days are required before a diagnosis of P multocida infection can be made from a bacteriological study, the infection can be successfully treated against febrile neutropenia with empirical cefepime. In a literature review, 7 cases, including ours, with hematological malignancies complicated with P multocida infection were identified and we summarized the clinical characteristics of these cases. These cases demonstrate the importance of the prevention of close contact between pet animals and immunocompromised hosts such as post-chemotherapy neutropenic patients.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Infecções por Pasteurella
/
Mordeduras e Picadas
/
Linfoma não Hodgkin
/
Cefalosporinas
/
Sulfatos de Condroitina
/
Fator Estimulador de Colônias de Granulócitos
/
Sepse
/
Dermatan Sulfato
/
Heparitina Sulfato
/
Antibacterianos
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Aged
/
Animals
/
Female
/
Humans
Idioma:
En
Revista:
Int J Hematol
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Japão