Emotion recognition and genetic vulnerability to schizophrenia.
Br J Psychiatry
; 191: 126-30, 2007 Aug.
Article
em En
| MEDLINE
| ID: mdl-17666496
ABSTRACT
BACKGROUND:
Epidemiological studies of schizophrenia suggest that this disorder has a substantial genetic component. Cognitive and social abilities, as well as the volumes of brain regions involved in emotion processing, have been found to be distributed along a continuum when comparing patients, siblings and controls, with siblings showing intermediate scores.AIMS:
To establish whether facial expression recognition is impaired in unaffected siblings of patients.METHOD:
Emotion and gender recognition were evaluated in a three-group pre-post study design in drug-naive patients with first-episode schizophrenia (n=40) and their unaffected siblings (n=30) compared with controls (n=26).RESULTS:
Patients and their healthy siblings showed impaired emotion recognition but normal gender recognition compared with controls. Patients'performance did not improve despite effective clinical stabilisation.CONCLUSIONS:
Impaired performance in healthy siblings and time stability in patients provides evidence of impairment of facial emotion recognition as an actual phenotype of schizophrenia.
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Base de dados:
MEDLINE
Assunto principal:
Transtornos da Percepção
/
Esquizofrenia
/
Transtornos Cognitivos
/
Emoções
/
Expressão Facial
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Br J Psychiatry
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
França