Effect of vitamin E on oxidative stress status in small intestine of diabetic rat.
World J Gastroenterol
; 13(32): 4340-4, 2007 Aug 28.
Article
em En
| MEDLINE
| ID: mdl-17708608
ABSTRACT
AIM:
To investigate the effect of vitamin E on oxidative stress status in the small intestine of diabetic rats.METHODS:
Twenty-four male Wistar rats were randomly divided into three groups Control (C), non-treated diabetic (NTD) and vitamin E-treated diabetic (V(E)TD) groups. The increases in lipid peroxidation, protein oxidation and superoxide dismutase (SOD) in these three groups was compared after 6 wk.RESULTS:
There was no significant difference in catalase activity between NTD and control rats. Compared to NTD rats, the treatment with vitamin E significantly decreased lipid peroxidation and protein oxidation, and also increased catalase activity and SOD.CONCLUSION:
The results revealed the occurrence of oxidative stress in the small intestine of diabetic rats. Vitamin E, as an antioxidant, attenuates lipid peroxidation and protein oxidation, and increases antioxidant defense mechanism.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vitamina E
/
Estresse Oxidativo
/
Diabetes Mellitus Experimental
/
Intestino Delgado
/
Antioxidantes
Limite:
Animals
Idioma:
En
Revista:
World J Gastroenterol
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Irã