Pulmonary and sinusal changes in 45 patients with primary immunodeficiencies: computed tomography evaluation.
J Comput Assist Tomogr
; 31(4): 620-8, 2007.
Article
em En
| MEDLINE
| ID: mdl-17882044
ABSTRACT
OBJECTIVE:
The aims of the study were 1) to identify and quantify pulmonary changes in subjects affected by agammaglobulinemia (AG), and common variable immunodeficiency (CVID) and 2) to assess the incidence, type, and degree of chronic sinusitis and their relation to pulmonary changes.METHODS:
Forty-five patients affected by AG (18) and CVID (27) underwent computed tomography of lungs and paranasal sinuses.RESULTS:
Of 45 patients, 26 (57.7%) had pulmonary changes, more frequent among CVID than AG patients (P = 0.37). Bronchiectases were detected in 7 of 12 AG and in 9 of 14 CVID; the difference is not statistically significant (P = 0.53). Computed tomographic findings of chronic sinusitis were detected in 41 of 45 patients. There was no statistically significant difference between AG and CVID patients. Bronchial and sinusal abnormalities did not correlate in 11 patients followed longitudinally.CONCLUSIONS:
On computed tomography, the type and severity of lung lesions do not correlate either with the type of immunodeficiency or with the severity of the sinusal involvement.
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Base de dados:
MEDLINE
Assunto principal:
Seios Paranasais
/
Tomografia Computadorizada por Raios X
/
Imunodeficiência de Variável Comum
/
Agamaglobulinemia
/
Pulmão
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Comput Assist Tomogr
Ano de publicação:
2007
Tipo de documento:
Article