Analgesic efficacy of orodispersible paracetamol in patients admitted to the emergency department with an osteoarticular injury.
Eur J Emerg Med
; 14(6): 337-42, 2007 Dec.
Article
em En
| MEDLINE
| ID: mdl-17968199
ABSTRACT
INTRODUCTION:
Acute pain still persists in patients under treatment after admission to emergency departments (ED). The objective of this study was to determine the efficacy of 1 g of paracetamol in patients presenting an osteoarticular injury. MATERIALS ANDMETHODS:
This prospective study included all patients admitted to the ED with an osteoarticular injury and a pain score above 30 on the visual analogue scale (VAS). Patients were selected on admission by the reception nurse and given paracetamol within 5 min of admission. VAS scores were recorded 30 and 60 min after admission. On discharge from the ED, the patients underwent a further VAS assessment and were asked a question about pain relief (yes/no answer). The primary endpoint was the VAS score at 60 min. The secondary endpoint was the pain relief expressed by the patient on discharge from the ED.RESULTS:
Five hundred and seventy-one patients were included. The median stay in the ED was 90 min (75-120 min). The diagnoses at discharge were sprain or dislocation (ankle, knee, and wrist) for 287 patients, fracture for 102 patients, and other injury for 182 patients. In 69% of the patients, the injured limb was immobilized. The median VAS score on admission was 57. A significant difference was seen between the median VAS on admission and at 1 h after admission (57+/-18 vs. 30+/-18; P<0.0001), and between the median VAS score at admission and the score at discharge from the ED (57+/-18 vs. 26+/-18, P<0.0001). Finally, 81% of the patients expressed pain relief. On discharge from the ED, a gain of 20 mm on the VAS had a positive predictive value of 93% [area under curve (AUC) 89; CI 86-92; P=0.001], for the endpoint 'patients stating pain relief'.CONCLUSION:
A simple and easily applicable protocol of pain management permits the achievement of satisfactory analgesia during a patient's stay in the ED.
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Base de dados:
MEDLINE
Assunto principal:
Dor
/
Ferimentos e Lesões
/
Osso e Ossos
/
Medição da Dor
/
Resultado do Tratamento
/
Analgésicos não Narcóticos
/
Serviço Hospitalar de Emergência
/
Articulações
/
Acetaminofen
Tipo de estudo:
Etiology_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Eur J Emerg Med
Assunto da revista:
MEDICINA DE EMERGENCIA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
França