Moderate hypoglycemia induces ultrastructural changes in perivascular nerve terminals of cat cerebral arteries.
Neurosci Lett
; 134(1): 67-70, 1991 Dec 16.
Article
em En
| MEDLINE
| ID: mdl-1815151
ABSTRACT
A quantitative morphological analysis of the perivascular nerve terminals of cerebral arteries during moderate hypoglycemia was performed. 5-Hydroxydopamine (5-OHDA) was applied to discriminate dense-cored vesicles, related to noradrenaline, and clear vesicles, related to acetylcholine, under the electron microscope. Five hypoglycemic and 5 normoglycemic cats, all receiving 5-OHDA, were compared. In both the middle cerebral artery and vertebral artery, the dense-cored vesicles were significantly smaller and clear vesicles were significantly larger in hypoglycemia than in normoglycemia. These morphological changes in the vesicles may indicate hyperactivity of the sympathetic system and hypoactivity of the parasympathetic system of the cerebral vessels during hypoglycemia.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Artérias Cerebrais
/
Hipoglicemia
/
Terminações Nervosas
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Neurosci Lett
Ano de publicação:
1991
Tipo de documento:
Article
País de afiliação:
Japão