A direct HPLC method for the resolution of glycidyl tosylate and glycidyl 3-nitrobenzenesulphonate enantiomers.

Shaw, C J; Barton, D L

Shaw, C J; Barton, D L.

Afiliação

Shaw CJ; R.W. Johnson Pharmaceutical Research Institute, Raritan, NJ 08869.

J Pharm Biomed Anal ; 9(10-12): 793-6, 1991.

Article em En | MEDLINE | ID: mdl-1822196

ABSTRACT

ABSTRACT

The enantiomeric composition of glycidyl tosylate and glycidyl 3-nitrobenzenesulphonate is obtained using an enantiomeric HPLC column. The chiral oxiranes were resolved on a cellulose carbamate column using a mobile phase of hexane 2-propanol. The method is simple, sensitive and does not require derivatization.

Assuntos

Benzenossulfonatos/análise; Nitrobenzenos/análise; Compostos de Tosil/análise; Cromatografia Líquida de Alta Pressão; Estereoisomerismo

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Base de dados: MEDLINE Assunto principal: Compostos de Tosil / Benzenossulfonatos / Nitrobenzenos Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 1991 Tipo de documento: Article

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