Anchoring the genome.
Genome Biol
; 9(1): 201, 2008 Jan 22.
Article
em En
| MEDLINE
| ID: mdl-18226181
ABSTRACT
Although the principles governing chromosomal architecture are largely unresolved, there is evidence that higher-order chromatin folding is mediated by the anchoring of specific DNA sequences to the nuclear matrix. These genome anchors are also crucial regulators of gene expression and DNA replication, and play a role in pathogenesis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Matriz Nuclear
/
Genoma
/
Montagem e Desmontagem da Cromatina
Idioma:
En
Revista:
Genome Biol
Assunto da revista:
BIOLOGIA MOLECULAR
/
GENETICA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido