Abdominal aortic aneurysm and cytomegalovirus infection.
J Med Virol
; 80(4): 667-9, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-18297722
ABSTRACT
Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal aortic aneurysm is unknown. The aim of the present study was to investigate whether CMV infection is related to abdominal aortic aneurysm rupture. One hundred nineteen patients with abdominal aortic aneurysm and 36 matched controls without abdominal aortic aneurysm were investigated prospectively by CMV serology. Patients with ruptured abdominal aortic aneurysm have similar levels of IgG antibodies against CMV as patients with nonruptured abdominal aortic aneurysm, small abdominal aortic aneurysm, and controls without abdominal aortic aneurysm. In conclusion, this study fails to demonstrate a connection between CMV infection and abdominal aortic aneurysm rupture.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ruptura Aórtica
/
Aneurisma da Aorta Abdominal
/
Infecções por Citomegalovirus
/
Aterosclerose
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Med Virol
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Suécia