Human and porcine neurocysticercosis: differences in the distribution and developmental stages of cysticerci.
Trop Med Int Health
; 13(5): 697-702, 2008 May.
Article
em En
| MEDLINE
| ID: mdl-18384482
ABSTRACT
OBJECTIVE:
To describe and compare the clinical impacts of neurocysticercosis (NC) caused by Taenia solium in humans and pigs.METHODS:
Comparative study of the brains of 16 asymptomatic pigs and 35 human NC cases (15 asymptomatic and 20 symptomatic).RESULTS:
In humans, cysticerci were more frequently located in the ventricles and subarachnoid space at the base of the brain (11.8%vs. 1.6%; P = 0.001 and 25.9%vs. 0%; P < 0.0001, respectively) while in pigs, cysticerci were more frequently found in the parenchyma (44.4%vs. 7.6%; P < 0.0001). In human brains, 75.9% of the cysticerci were calcified, while in pigs all cysticerci were in the vesicular stage.CONCLUSION:
The duration of infection and the host-parasite relationship (such as immune reactivity and brain haemodynamics) differ between humans and pigs. This may account for the different distribution and stage of the cysticerci among humans and pigs.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Suínos
/
Encefalopatias
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Neurocisticercose
/
Taenia solium
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trop Med Int Health
Assunto da revista:
MEDICINA TROPICAL
/
SAUDE PUBLICA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
México